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A terraced house in east London went up in flames after a dramatic explosion on Tuesday afternoon. Around 60 and eight engines were called to the blaze on Ley Street in just after 4pm, which caused the house’s first floor and loft conversion to go up in flames. Social media footage from the scene appeared to show an explosion at the house as shocked residents scrambled to call the emergency services. House explodes on Ley Street in Ilford 😳 — INSTA: IG1IG3 (@Ig1Ig3) Station Commander Darren McTernan said: "Firefighters worked hard to bring this fire under control. Crews will remain on scene throughout the evening. "Ley Street remains closed between Eastern Avenue and Vicarage Road, impacting traffic in the surrounding area, so please continue to avoid the area if you can. "One of the Brigade's 32-metre turntable ladders was used at the scene as a water tower to help fight the fire from above. “The Brigade's drone team were also deployed to the incident, offering the Incident Commander an aerial view of the scene." The brigade said it took the first of 25 calls regarding the fire at 4.09pm and mobilised crews from Ilford, Dagenham, Barking and surrounding fire stations to the scene. The fire was under control by 6.23pm. A Met Police spokesperson said: “Police were called at 4.08pm on 10 December to reports of a fire at a residential property in Ley Street, Ilford. “We have attended alongside the London Fire Brigade and London Ambulance Service. “We remain at the scene and cordons are in place.” Jas Athwal, MP for Ilford South, wrote on X: “Please be aware there is an ongoing fire in a residential property on Ley Street in Ilford. “London Fire Brigade & Redbridge Borough Police are on the scene. People are advised to stay away from the area while the emergency services attend.” Councillor Khayer Chowdhury, cabinet member for enforcement and community safety on Redbridge Council, added: “We're on standby to provide support to with the clear up operation. “We're also on standby to support residents who have been directly affected by this incident and will be liaising with our Fire Brigade & Redbridge Borough Police partners.” The cause of the fire is not yet known and is under investigation.ssbet777

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Scottsdale police have released surveillance video of a brawl involving former NHL player Paul Bissonnette and six men at a Houston’s restaurant on Nov. 24, which resulted in him being hospitalized. In the footage, posted to social media by 12News, Bissonnette is shirtless and chased through a parking lot while several men pursue him — eventually ganging up to punch and kick him multiple times on the ground before he’s able to escape. “This is the worst of it I took after I knock out that inbred William Carroll f–k before we pass the dumpster,” the Barstool Sports podcaster wrote on X . “It was never going to be a fair fight. Let the games begin. Ate some boot f–ks to the head & jaw but wouldn’t change a thing. F–k the Scottsdale Six. This ain’t over.” The Scottsdale Police Department arrested the six men — Henry Mesker, John Carroll, William Carroll, Danny Bradley, Edward Jennings and Sean Daley — and released their mugshots on Nov. 26. Some of the men were seen with bruises on their face in the mugshot photos. All six men were hit with assault charges, and some received an additional charge of disorderly conduct, according to court documents obtained by TMZ Sports. Daley, 29, was charged with a felony count of possession of a forged instrument after police said he admitted he had a fraudulent military ID on his person at the time of his arrest. Daley is due back in court for another hearing sometime this month. A day after the incident, Bissonnette, 39, posted a video on social media alleging he was attacked by a bunch of “drunk golfers” while at Houston’s, and the brawl spilled into a CVS parking lot nearby. The “NHL on TNT” analyst explained he “felt the need to step in” when he saw the men getting physical with the restaurant staff at that Houston’s location, which he visits three or four times a week. “I ate three kicks, one in the neck and two in the head,” he said on Barstool Sports’ “Spittin’ Chiclets” podcast, in the aftermath, adding that his shirt was ripped off and he lost his shoes. The six men were involved in another altercation at the nearby Raven Golf Club just hours earlier, according to a separate video shared on social media by Shea Stevens. Bissonnette previously said the altercation was captured on camera and that he was waiting for the footage to come out. The ex- NHLer vowed to seek vengeance on the six men. “It was a bunch of drunk golfers, things obviously continued to escalate,” he said in a video on X last month. “They asked one guy to leave. And then one guy kept getting in the manager’s face and put his hands on him. “... I went over I just grabbed the guy’s arm that was on him and I said, ‘Sir if you continue to harass and assault this staff, we’re going to have problems,’ and then they just started chucking.”

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Clinical and regulatory success in 2024 expected to drive value in 2025 CRANFORD, N.J. , Dec. 27, 2024 /PRNewswire/ -- Citius Pharmaceuticals, Inc. ("Citius Pharma" or the "Company") (Nasdaq: CTXR), a biopharmaceutical company dedicated to the development and commercialization of first-in-class critical care products today reported business and financial results for the fiscal full year ended September 30, 2024 . Fiscal Full Year 2024 Business Highlights and Subsequent Developments Achieved U.S. Food and Drug Administration (FDA) approval of LYMPHIRTM (denileukin diftitox-cxdl), an immunotherapy for the treatment of adults with relapsed or refractory cutaneous T-cell lymphoma (CTCL); Advanced manufacturing, marketing and sales activities in preparation for commercial launch of LYMPHIR in the first half of 2025; Completed the merger of Citius Pharma's oncology subsidiary with TenX Keane to form Citius Oncology, Inc., a standalone publicly traded company which began trading on the Nasdaq exchange under the ticker symbol CTOR on August 13, 2024 ; Supported two investigator-initiated trials to explore LYMPHIR's potential as an immuno-oncology combination therapy being conducted at the University of Pittsburgh Medical Center and the University of Minnesota ; Shared interim trial results with the clinical community at the Society for Immunotherapy of Cancer Conference (SITC) of University of Pittsburgh Medical Center's Phase I trial of LYMPHIR with checkpoint inhibitor pembrolizumab; and, Met primary and secondary endpoints in the Phase 3 Pivotal Trial of Mino-Lok ® , demonstrating a statistically significant improvement in time to catheter failure of infected catheters compared to other physician-selected anti-infective lock solutions. Financial Highlights Cash and cash equivalents of $3.3 million as of September 30, 2024 ; R&D expenses were $11.9 million for the full year ended September 30, 2024 , compared to $14.8 million for the full year ended September 30, 2023 ; G&A expenses were $18.2 million for the full year ended September 30, 2024 , compared to $15.3 million for the full year ended September 30, 2023 ; Stock-based compensation expense was $11.8 million for the full year ended September 30, 2024 , compared to $6.6 million for the full year ended September 30, 2023 ; and, Net loss was $39.4 million , or ($5.97) per share for the full year ended September 30, 2024 compared to a net loss of $32.5 million , or ($5.57) per share for the full year ended September 30, 2023 . "In fiscal year 2024 we drove tremendous progress in our pipeline. It was a transformative year, marked by our first FDA approval and significant clinical milestones. The approval of LYMPHIRTM and the positive Phase 3 results for Mino-Lok® underscore our commitment to developing innovative therapies. Our team successfully responded to FDA comments related to the biologics license application for LYMPHIR and ultimately gained FDA approval. Productive engagement with the FDA regarding the positive results of our Phase 3 Mino-Lok® trial and Phase 2 Halo-Lido trial clarified our next steps for both programs. We anticipate continued engagement with the agency in the coming year and look forward to their guidance. Additionally, we are exploring strategic partnerships and licensing opportunities to maximize the potential of our portfolio and bring these important therapies to market efficiently," stated Leonard Mazur , Chairman and CEO of Citius Pharma. "Looking ahead, our priorities for fiscal year 2025 include launching LYMPHIRTM through our majority-owned subsidiary, Citius Oncology, driving the clinical and regulatory strategies for Mino-Lok® and Halo-Lido, fortifying our financial position, and applying a disciplined approach to resource allocation. We expect to launch LYMPHIR in the first half of 2025 and distribute CTOR shares to Citius Pharma shareholders by the end of the year, pending favorable market conditions. Our goal remains to deliver value for patients, healthcare providers, and shareholders. With a clear vision and a strong team, we are well-positioned to execute on our mission of bringing innovative therapies to market," added Mazur. FULL YEAR 2024 FINANCIAL RESULTS: Liquidity As of September 30, 2024 , the Company had $3.3 million in cash and cash equivalents. As of September 30, 2024 , the Company had 7,247,243 common shares outstanding, as adjusted for the 1-for-25 reverse stock split of the Company's common stock, effected on November 25, 2024 . During the year ended September 30, 2024 , the Company received net proceeds of $13.8 million from the issuance of equity. The Company expects to raise additional capital to support operations. Research and Development (R&D) Expenses R&D expenses were $11.9 million for the full year ended September 30, 2024 , compared to $14.8 million for the full year ended September 30, 2023 . The decrease in R&D expenses primarily reflects the completion of the Halo-Lido trial and completion of activities related to the regulatory resubmission for LYMPHIR, offset by shutdown costs associated with the end of the Phase 3 trial for Mino-Lok. We expect research and development expenses to decrease in fiscal year 2025 as we continue to focus on the commercialization of LYMPHIR through our majority-owned subsidiary, Citius Oncology and because we have completed the Phase 3 trial for Mino-Lok. General and Administrative (G&A) Expenses G&A expenses were $18.2 million for the full year ended September 30, 2024 , compared to $15.3 million for the full year ended September 30, 2023 . The increase was primarily due to costs associated with pre-launch and market research activities associated with LYMPHIR. General and administrative expenses consist primarily of compensation costs, professional fees for legal, regulatory, accounting and corporate development services, and investor relations expenses. Stock-based Compensation Expense For the full year ended September 30, 2024 , stock-based compensation expense was $11.8 million as compared to $6.6 million for the prior year. The increase of $5.2 million is largely due to the grant of options under the Citius Oncology stock plan. Stock-based compensation expense under the Citius Oncology stock plan was $7.5 million during the year ended September 30, 2024 , compared to $2.0 million for the year ended September 30, 2023 , as the plan was initiated in July 2023 . For the years ended September 30, 2024 and 2023, stock-based compensation expense also includes $47,547 and $130,382 , respectively, for the NoveCite stock option plan. In fiscal years 2023 and 2024, we granted options to our new employees and additional options to other employees, our directors, and consultants. Net loss Net loss was $39.4 million , or ($5.97) per share for the year ended September 30, 2024 , compared to a net loss of $32.5 million , or ($5.57) per share for the year ended September 30, 2023 , as adjusted for the reverse stock split. The increase in net loss reflects an increase in operating expense of $5.3 million offset by a decrease of $1.6 million in other income. Operating expense increased due to increases in stock-based compensation and general and administrative expenses, which were offset by decreased research and development expense. About Citius Pharmaceuticals, Inc. Citius Pharma is a biopharmaceutical company dedicated to the development and commercialization of first-in-class critical care products. In August 2024 , the FDA approved LYMPHIRTM, a targeted immunotherapy for an initial indication in the treatment of cutaneous T-cell lymphoma. Citius Pharma's late-stage pipeline also includes Mino-Lok®, an antibiotic lock solution to salvage catheters in patients with catheter-related bloodstream infections, and CITI-002 (Halo-Lido), a topical formulation for the relief of hemorrhoids. A Pivotal Phase 3 Trial for Mino-Lok and a Phase 2b trial for Halo-Lido were completed in 2023. Mino-Lok met primary and secondary endpoints of its Phase 3 Trial. Citius Pharma is actively engaged with the FDA to outline next steps for both programs. For more information, please visit www.citiuspharma.com . Forward-Looking Statements This press release may contain "forward-looking statements" within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934. Such statements are made based on our expectations and beliefs concerning future events impacting Citius Pharma. You can identify these statements by the fact that they use words such as "will," "anticipate," "estimate," "expect," "plan," "should," and "may" and other words and terms of similar meaning or use of future dates. Forward-looking statements are based on management's current expectations and are subject to risks and uncertainties that could negatively affect our business, operating results, financial condition and stock price. Factors that could cause actual results to differ materially from those currently anticipated, and, unless noted otherwise, that apply to Citius Pharma are: our ability to raise additional money to fund our operations for at least the next 12 months as a going concern; our ability to commercialize LYMPHIR through our majority-owned subisity and any of our other product candidates that may be approved by the FDA; the estimated markets for our product candidates and the acceptance thereof by any market; the ability of our product candidates to impact the quality of life of our target patient populations; risks related to research using our assets but conducted by third parties; risks relating to the results of research and development activities, including those from our existing and any new pipeline assets; our ability to maintain compliance with Nasdaq's continued listing standards; our dependence on third-party suppliers; our ability to procure cGMP commercial-scale supply; our ability to obtain, perform under and maintain financing and strategic agreements and relationships; uncertainties relating to preclinical and clinical testing; the early stage of products under development; market and other conditions; risks related to our growth strategy; patent and intellectual property matters; our ability to identify, acquire, close and integrate product candidates and companies successfully and on a timely basis; government regulation; competition; as well as other risks described in our Securities and Exchange Commission ("SEC") filings. These risks have been and may be further impacted by any future public health risks. Accordingly, these forward-looking statements do not constitute guarantees of future performance, and you are cautioned not to place undue reliance on these forward-looking statements. Risks regarding our business are described in detail in our SEC filings which are available on the SEC's website at www.sec.gov , including in Citius Pharma's Annual Report on Form 10-K for the year ended September 30, 2024 , filed with the SEC on December 27, 2024 , as updated by our subsequent filings with the SEC. These forward-looking statements speak only as of the date hereof, and we expressly disclaim any obligation or undertaking to release publicly any updates or revisions to any forward-looking statements contained herein to reflect any change in our expectations or any changes in events, conditions or circumstances on which any such statement is based, except as required by law. Investor Contact: Ilanit Allen ir@citiuspharma.com 908-967-6677 x113 Media Contact: STiR-communications Greg Salsburg Greg@STiR-communications.com -- Financial Tables Follow – CITIUS PHARMACEUTICALS, INC. CONSOLIDATED BALANCE SHEETS SEPTEMBER 30, 2024 AND 2023 2024 2023 ASSETS Current Assets: Cash and cash equivalents $ 3,251,880 $ 26,480,928 Inventory 8,268,766 — Prepaid expenses 2,700,000 7,889,506 Total Current Assets 14,220,646 34,370,434 Property and equipment, net — 1,432 Operating lease right-of-use asset, net 246,247 454,426 Other Assets: Deposits 38,062 38,062 In-process research and development 92,800,000 59,400,000 Goodwill 9,346,796 9,346,796 Total Other Assets 102,184,858 68,784,858 Total Assets $ 116,651,751 $ 103,611,150 LIABILITIES AND STOCKHOLDERS' EQUITY Current Liabilities: Accounts payable $ 4,927,211 $ 2,927,334 License payable 28,400,000 — Accrued expenses 17,027 476,300 Accrued compensation 2,229,018 2,156,983 Operating lease liability 241,547 218,380 Total Current Liabilities 35,814,803 5,778,997 Deferred tax liability 6,713,800 6,137,800 Operating lease liability – non current 21,318 262,865 Total Liabilities 42,549,921 12,179,662 Commitments and Contingencies Stockholders' Equity: Preferred stock - $0.001 par value; 10,000,000 shares authorized; no shares issued and outstanding — — Common stock - $0.001 par value; 16,000,000 shares authorized; 7,247,243 and 6,354,371 shares issued and outstanding at September 30, 2024 and 2023, respectively 7,247 6,354 Additional paid-in capital 271,440,421 253,056,133 Accumulated deficit (201,370,218) (162,231,379) Total Citius Pharmaceuticals, Inc. Stockholders' Equity 70,077,450 90,831,108 Non-controlling interest 4,024,380 600,380 Total Equity 74,101,830 91,431,488 Total Liabilities and Equity $ 116,651,751 $ 103,611,150 Reflects a 1-for-25 reverse stock split effective November 25, 2024. CITIUS PHARMACEUTICALS, INC. CONSOLIDATED STATEMENTS OF OPERATIONS FOR THE YEARS ENDED SEPTEMBER 30, 2024 AND 2023 2024 2023 Revenues $ — $ — Operating Expenses: Research and development 11,906,601 14,819,729 General and administrative 18,249,402 15,295,584 Stock-based compensation – general and administrative 11,839,678 6,616,705 Total Operating Expenses 41,995,681 36,732,018 Operating Loss (41,995,681) (36,732,018) Other Income: Interest income, net 758,000 1,179,417 Gain on sale of New Jersey net operating losses 2,387,842 3,585,689 Total Other Income Net 3,145,842 4,765,106 Loss before Income Taxes (38,849,839) (31,966,912) Income tax expense 576,000 576,000 Net Loss (39,425,839) (32,542,912) Net loss attributable to non-controlling interest 287,000 - Deemed dividend on warrant extension (1,047,312) (1,151,208) Net Loss Applicable to Common Stockholders $ (40,186,151) (33,694,120) Net Loss Per Share Applicable to Common Stockholders - Basic and Diluted $ (5.97) (5.57) Weighted Average Common Shares OutstandingPHILADELPHIA (AP) — Former Temple basketball standout Hysier Miller sat for a long interview with the NCAA as it looked into concerns about unusual gambling activity, his lawyer said Friday amid reports a federal probe is now under way. “Hysier Miller fully cooperated with the NCAA’s investigation. He sat for a five-hour interview and answered every question the NCAA asked. He also produced every document the NCAA requested,” lawyer Jason Bologna said in a statement. “Hysier did these things because he wanted to play basketball this season, and he is devastated that he cannot.” Miller, a three-year starter from South Philadelphia, transferred to Virginia Tech this spring. However, the Hokies released him last month due to what the program called “circumstances prior to his enrollment at Virginia Tech.” Bologna declined to confirm that a federal investigation had been opened, as did spokespeople for both the FBI and the U.S. Attorney’s Office in Philadelphia. ESPN, citing unnamed sources, reported Thursday that authorities were investigating whether Miller bet on games he played in at Temple, and whether he adjusted his performance accordingly. “Hysier Miller has overcome more adversity in his 22 years than most people face in their lifetime. He will meet and overcome whatever obstacles lay ahead," Bologna said. Miller scored eight points — about half his season average of 15.9 — in a 100-72 loss to UAB on March 7 that was later flagged for unusual betting activity. Temple said it has been aware of those allegations since they became public in March, and has been cooperative. “We have been fully responsive and cooperative with the NCAA since the moment we learned of the investigation,” Temple President John Fry said in a letter Thursday to the school community. However, Fry said Temple had not received any requests for information from state or federal law enforcement agencies. He vowed to cooperate fully if they did. “Coaches, student-athletes and staff members receive mandatory training on NCAA rules and regulations, including prohibitions on involvement in sports wagering," Fry said in the letter. The same week the Temple-UAB game raised concerns, Loyola (Maryland) said it had removed a person from its basketball program after it became aware of a gambling violation. Temple played UAB again on March 17, losing 85-69 in the finals of the American Athletic Conference Tournament. League spokesman Tom Fenstermaker also declined comment on Friday. Get poll alerts and updates on the AP Top 25 throughout the season. Sign up here . AP college basketball: https://apnews.com/hub/ap-top-25-college-basketball-poll and https://apnews.com/hub/college-basketball

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